Telmisartan/amlodipine (By mouth)
Amlodipine (am-LOE-di-peen), Telmisartan (tel-mi-SAR-tan)
Treats high blood pressure. Lowering blood pressure reduces the risk of strokes and heart attacks. This medicine is a combination of an angiotensin receptor blocker and a calcium channel blocker.
TwynstaThere may be other brand names for this medicine.
When This Medicine Should Not Be Used:You should not use this medicine if you have had an allergic reaction to telmisartan or amlodipine, or if you are pregnant.
How to Use This Medicine:
- Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.
- You may take this medicine with or without food.
- Carefully follow your doctor's instructions about any special diet.
- Take this medicine at the same time each day.
- This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.
If a dose is missed:
- If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine:
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Protect the tablets from moisture and do not remove from the blister pack until you are ready to use them.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you are also using other medicines for high blood pressure (such as enalapril, lisinopril, ramipril, Accupril®, Altace®, Lotrel®, or Zestril®) or a diuretic or "water pill" (such as amiloride, furosemide, hydrochlorothiazide, spironolactone, torsemide, triamterene, Aldactone®, Demadex®, Dyrenium®, Lasix®, or Midamor®).
- Make sure your doctor knows if you are also using digoxin (Digitek®, Lanoxin®), lithium (Eskalith®, Lithobid®), or pain or arthritis medicine called "NSAIDs" (such as aspirin, celecoxib, ibuprofen, naproxen, Advil®, Aleve®, Celebrex®, or Motrin®).
- Ask your doctor before you use potassium supplements or salt substitutes that contain potassium.
Warnings While Using This Medicine:
- Using this medicine while you are pregnant (especially in your second or third trimester) can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using this medicine, tell your doctor right away.
- Make sure your doctor knows if you are breastfeeding, or if you have kidney problems, liver disease, chest pain, congestive heart failure, heart or blood vessel problems, a mineral imbalance (such as high potassium or low sodium in the blood), or a recent heart attack. Tell your doctor if you are dehydrated or have recently had severe diarrhea or vomiting. Tell your doctor if you are receiving dialysis.
- This medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life.
- This medicine may make you feel lightheaded, dizzy, or faint, especially when you get up suddenly from a lying position. Getting up slowly may help. Also, avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
- Check with your doctor right away if you become sick while taking this medicine, especially with severe or continuing nausea, vomiting, or diarrhea. These conditions may cause you to lose too much water or salt.
- Check with your doctor right away if you experience dizziness, fainting, confusion, muscle pain, weakness, and/or a fast heartbeat. Use extra care if you exercise or if the weather is hot. Heavy sweating can cause dehydration (loss of too much water) or electrolyte imbalances (loss of sodium or potassium in the body).
- This medicine may worsen the symptoms of angina (chest pain) or a heart attack in certain patients with severe heart or blood vessel disease. Check with your doctor right away if you are having chest pain or discomfort; fast or irregular heartbeat; nausea or vomiting; pain or discomfort in the arms, jaw, back, or neck; shortness of breath; or sweating.
- Check with your doctor right away if you have swelling of your hands, ankles, or feet, or gained weight while taking this medicine. These may be symptoms of your kidney problems getting worse.
- If you stop using this medicine, your blood pressure may go up. High blood pressure usually has no symptoms. Even if you feel well, do not stop using this medicine without asking your doctor.
- Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments. Blood tests may be needed to check for unwanted effects.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, or red skin rash.
- Blood in the urine, lower back pain, side pain, or sharp back pain just below the ribs.
- Change in how much or how often you urinate.
- Chest pain.
- Confusion, weakness, shortness of breath, or numbness or tingling in your hands, feet, or lips.
- Dark-colored urine or pale stools.
- Fast, pounding, or uneven heartbeat.
- Fever, chills, cough, sore throat, stuffy or runny nose, and body aches.
- Lightheadedness, dizziness, or fainting.
- Muscle pain, tenderness, or weakness.
- Rapid weight gain.
- Swelling in your hands, ankles, or feet.
- Warmth or redness in your face, neck, arms, or upper chest.
- Yellowing of your skin or the whites of your eyes.
If you notice these less serious side effects, talk with your doctor:
- Back pain.
- Diarrhea, nausea, stomach pain, or upset stomach.
- Mild skin rash.
- Sleepiness or unusual drowsiness.
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088Last Updated:
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