Sumatriptan (Into the nose)
Treats migraine headaches. This medicine is not used to prevent migraines. It belongs to a group of medicines called triptans.
ImitrexThere may be other brand names for this medicine.
When This Medicine Should Not Be Used:You should not use this medicine if you have had an allergic reaction to sumatriptan. Do not use this medicine if you have a history of heart disease, heart attack, angina (chest pain), stroke, transient ischemic attack (TIA), ischemic bowel disease, peripheral vascular disease, or severe liver disease. You should not use this medicine if you have uncontrolled high blood pressure or hemiplegic or basilar migraine headaches. Do not use this medicine if you have used an MAO inhibitor (MAOI) such as isocarboxazid (Marplan®), phenelzine (Nardil®), selegiline (Eldepryl®), or tranylcypromine (Parnate®) within the past 14 days. Do not use this medicine if you have used other triptan or ergot-type migraine medicines within the past 24 hours. Some examples of triptan medicines are naratriptan (Amerge®), sumatriptan (Imitrex®, Treximet®), and zolmitriptan (Zomig®). Some examples of ergot-type medicines are dihydroergotamine (D.H.E. 45®, Migranal®) and ergotamine (Bellergal®, Cafergot®, Ergomar®, or Wigraine®).
How to Use This Medicine:
- Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
- Unless your doctor tells you otherwise, use this medicine in only one nostril for each dose.
- This medicine is for use only in the nose. Do not get any of it in your eyes or on your skin. If it does get on these areas, rinse it off right away.
- This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.
How to Store and Dispose of This Medicine:
- Keep the bottle tightly closed when not using it. Store at room temperature, away from heat and direct light.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you are also using medicine for depression (such as citalopram, duloxetine, fluoxetine, fluvoxamine, paroxetine, sertraline, trazodone, venlafaxine, Celexa®, Effexor®, Luvox®, Paxil®, Prozac®, Serzone®, or Zoloft®).
Warnings While Using This Medicine:
- Make sure your doctor knows if you are pregnant or planning to become pregnant. Your doctor may want you to join a pregnancy registry for patients using this medicine.
- Make sure your doctor knows if you have kidney disease, liver disease, high blood pressure, high cholesterol in the blood, diabetes, epilepsy, or a family history of coronary artery disease. Tell your doctor if you have a history of stomach or bowel bleeding, stroke, or Raynaud syndrome.
- Do not breastfeed for 12 hours after using this medicine.
- This medicine may increase your risk of having a heart attack, angina, or stroke. This is more likely to occur if you or a family member already have heart disease, if you smoke, if you are male and over 40 years of age, or if you are female and have gone through menopause. Call your doctor right away if you have any symptoms of a heart problem, such as chest pain or discomfort; an irregular heartbeat; nausea or vomiting; pain or discomfort in the shoulders, arms, jaw, back, or neck; shortness of breath; or sweating. Call your doctor right away if you have any symptoms of a stroke, such as confusion; difficulty with speaking; double vision; headaches; an inability to move the arms, legs, or facial muscles; an inability to speak; or slow speech.
- You should not use this medicine if your headache symptoms are different from the symptoms you usually have with a migraine headache. If you have a severe headache and do not know the cause, call your doctor. Check with your doctor if you used this medicine and your migraine did not go away, or if your migraine got worse or started occurring more often.
- This medicine may cause a serious condition called serotonin syndrome when taken with certain medicines. Check with your doctor first before taking any other medicines. Check with your doctor right away if you have agitation; confusion; diarrhea; excitement while talking that is not normal; fever; overactive reflexes; poor coordination; restlessness; shivering; sweating; trembling or shaking that you cannot control; or twitching. These could be symptoms of serotonin syndrome.
- Check with your doctor right away if you have blurred vision, difficulty with reading, or any other change in vision while you are using this medicine. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).
- This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis requires immediate medical attention. The most serious signs of this reaction are very fast or irregular breathing, gasping for breath, wheezing, or fainting. Other signs may include changes in color of the skin of the face; very fast but irregular heartbeat or pulse; hive-like swellings on the skin; and puffiness or swelling of the eyelids or around the eyes. If these side effects occur, get emergency help at once.
- This medicine may make you dizzy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
- Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blurred or decreased vision.
- Fast, pounding, or uneven heartbeat.
- Numbness or tingling in your hands, arms, legs, or feet.
- Stomach pain, diarrhea, or blood in your stools.
- Tightness or discomfort in your chest, neck, or jaw.
If you notice these less serious side effects, talk with your doctor:
- Bad or unusual taste in your mouth.
- Burning, numbness, tingling, or pain in your nose.
- Discomfort in your throat.
- Feeling dizzy or lightheaded.
- Nausea or vomiting.
- Runny nose.
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088Last Updated:
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